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Sclerostin Antikörper (Middle Region)

SOST Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN358752
  • Target Alle Sclerostin (SOST) Antikörper anzeigen
    Sclerostin (SOST)
    Bindungsspezifität
    • 15
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 141-171, Middle Region
    Reaktivität
    • 69
    • 52
    • 35
    • 16
    • 15
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 71
    • 3
    • 2
    • 1
    Kaninchen
    Klonalität
    • 72
    • 5
    Polyklonal
    Konjugat
    • 29
    • 7
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Sclerostin Antikörper ist unkonjugiert
    Applikation
    • 74
    • 35
    • 28
    • 24
    • 13
    • 11
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody recognizes SOST (Center).
    Aufreinigung
    Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide between 141~171 amino acids from the Center region of Human SOST.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SOST Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western Blot: 1/50-1/100Immunohistochemistry: 1/10-1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    Sclerostin (SOST)
    Andere Bezeichnung
    Sclerostin / SOST (SOST Produkte)
    Synonyme
    LOC100313724 antikoerper, CDD antikoerper, VBCH antikoerper, 5430411E23Rik antikoerper, sclerostin antikoerper, LOC100313724 antikoerper, SOST antikoerper, Sost antikoerper
    Hintergrund
    Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of the sclerostin gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
    Gen-ID
    50964, 9606
    UniProt
    Q9BQB4
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