MMP15 Antikörper (N-Term)

Produktnummer ABIN358688

Der Kaninchen Polyklonal anti-MMP15 Antikörper wird verwendet zum Nachweis von MMP15 in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für MMP15 Antikörper (N-Term) (ABIN358688)

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MMP15 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to MMP15.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MMP15.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu MMP15

Target: MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))

Andere Bezeichnung: MMP-15

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP15 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.Synonyms: MMP15, MT-MMP 2, MT2-MMP, MT2MMP, MTMMP2, Matrix metalloproteinase-15, Membrane-type matrix metalloproteinase 2, Membrane-type-2 matrix metalloproteinase, SMCP-2

Gen-ID: 4324, 5874

UniProt: P51511