S1PR1 Antikörper (N-Term)

Produktnummer ABIN358616

Produktdetails anti-S1PR1 Antikörper

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S1PR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to EDG1.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human EDG1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu S1PR1

Target: S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))

Andere Bezeichnung: EDG-1 / S1PR1 (S1PR1 Produkte)

Synonyme: CD363 antikoerper, CHEDG1 antikoerper, D1S3362 antikoerper, ECGF1 antikoerper, EDG-1 antikoerper, EDG1 antikoerper, S1P1 antikoerper, AI849002 antikoerper, Edg1 antikoerper, Lpb1 antikoerper, S1p antikoerper, S1p1 antikoerper, S1P receptor 1 antikoerper, S1P receptor Edg-1 antikoerper, edg1 antikoerper, etID43307.22 antikoerper, s1p1 antikoerper, wu:fb98f05 antikoerper, s1pr1 antikoerper, xts1p1 antikoerper, sphingosine-1-phosphate receptor 1 antikoerper, sphingosine-1-phosphate receptor 1 L homeolog antikoerper, S1PR1 antikoerper, S1pr1 antikoerper, s1pr1 antikoerper, s1pr1.L antikoerper

Hintergrund: EDG1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion.Synonyms: CHEDG1, D1S3362, ECGF1, EDG1, Endothelial differentiation G-protein coupled receptor 1, FLJ58121, S1P receptor 1, S1PR1, Sphingosine 1-phosphate receptor 1

Gen-ID: 1901, 9606

UniProt: P21453

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2