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TNK2 Antikörper (pTyr518)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TNK2 in EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN358513

Kurzübersicht für TNK2 Antikörper (pTyr518) (ABIN358513)

Target

Alle TNK2 Antikörper anzeigen
TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

Reaktivität

  • 119
  • 61
  • 50
  • 3
  • 2
  • 2
Human

Wirt

  • 115
  • 4
  • 1
Kaninchen

Klonalität

  • 117
  • 2
Polyklonal

Konjugat

  • 49
  • 8
  • 8
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser TNK2 Antikörper ist unkonjugiert

Applikation

  • 86
  • 54
  • 26
  • 26
  • 22
  • 16
  • 15
  • 11
  • 10
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 26
    • 15
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr518

    Spezifität

    This antibody detects TNK2 / ACK1 pTyr518.

    Aufreinigung

    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    TNK2 (tyrosine Kinase, Non-Receptor, 2 (TNK2))

    Andere Bezeichnung

    TNK2 / ACK1

    Hintergrund

    ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Synonyms: Activated CDC42 kinase 1

    Molekulargewicht

    114327 Da

    Gen-ID

    10188, 9606

    UniProt

    Q07912
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