ITGB1BP3 Antikörper (N-Term)

Produktnummer ABIN357956

Der Kaninchen Polyklonal anti-ITGB1BP3 Antikörper wird verwendet zum Nachweis von ITGB1BP3 in Proben von Human. Er wurde validiert für IHC (p) und EIA.

Kurzübersicht für ITGB1BP3 Antikörper (N-Term) (ABIN357956)

Target: ITGB1BP3 (Integrin beta 1 Binding Protein 3 (ITGB1BP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGB1BP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-ITGB1BP3 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects ITGB1BP3 (N-term).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human ITGB1BP3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ITGB1BP3

Target: ITGB1BP3 (Integrin beta 1 Binding Protein 3 (ITGB1BP3))

Andere Bezeichnung: ITGB1BP3 / NRK2

Hintergrund: ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.Synonyms: Integrin beta-1-binding protein 3, MIBP, Muscle integrin-binding protein, Nicotinamide riboside kinase 2, Nicotinic acid riboside kinase 2, NmR-K2, RNK2, Ribosylnicotinamide kinase 2, Ribosylnicotinic acid kinase 2

Molekulargewicht: 26046 Da

Gen-ID: 27231, 9606

UniProt: Q9NPI5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development