ACSL6 Antikörper (Middle Region)

Produktnummer ABIN357782

Der Kaninchen Polyklonal Anti-ACSL6-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, ACSL6 in Proben von Human und Maus zu detektieren.

Kurzübersicht für ACSL6 Antikörper (Middle Region) (ABIN357782)

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-ACSL6 Antikörper

Bindungsspezifität: Middle Region

Spezifität: This antibody is specific to FACL6 (Center).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FACL6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ACSL6

Target: ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6 (ACSL6))

Andere Bezeichnung: ACSL6

Hintergrund: FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5,12)(q31,p13) that involves ETV6 and ACSL6.Synonyms: ACS2, FACL6, KIAA0837, LACS5, Long-chain acyl-CoA synthetase 6, Long-chain-fatty-acid--CoA ligase 6

Molekulargewicht: 77680 Da

Gen-ID: 23305, 5874

UniProt: Q9UKU0