MARCKS Antikörper (C-Term)
Kurzübersicht für MARCKS Antikörper (C-Term) (ABIN357762)
Target
Alle MARCKS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 247-276, C-Term
-
Spezifität
- This antibody is specific to Human MARCKS (C-term).
-
Aufreinigung
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
-
Immunogen
- KLH conjugated synthetic peptide between 247~276 amino acids from the C-terminal region of human MARCKS
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
-
ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.25 mg/mL
-
Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
-
- MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))
-
Andere Bezeichnung
- MARCKS
-
Hintergrund
- MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL
-
Molekulargewicht
- 31413 Da
-
Gen-ID
- 4082
-
NCBI Accession
- NP_002347
-
UniProt
- P29966
Target
-