CBX8 Antikörper (C-Term)

Produktnummer ABIN357753

Produktdetails anti-CBX8 Antikörper

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to CBX8 (C-term).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CBX8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Andere Bezeichnung: CBX8 (CBX8 Produkte)

Synonyme: cbx8 antikoerper, MGC147589 antikoerper, Pc3 antikoerper, PC3 antikoerper, RC1 antikoerper, chromobox 8 antikoerper, chromobox 8 S homeolog antikoerper, chromobox homolog 8a (Pc class homolog, Drosophila) antikoerper, cbx8 antikoerper, CBX8 antikoerper, Cbx8 antikoerper, cbx8.S antikoerper, cbx8a antikoerper

Hintergrund: Chromobox homolog 8 (CBX8 or Pc3) is a member of Drosophila Polycomb group gene family. The polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators and thus are essential for proper development. Changes in expression of PcG proteins have been associated with cancer. CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility. Structurally, CBX4 contains 1 chromo domain, which is 40 to 50 amino acids long.Synonyms: Chromobox protein homolog 8, PC3, Polycomb 3 homolog, RC1, Rectachrome 1

Molekulargewicht: 43437 Da

Gen-ID: 57332, 9606

UniProt: Q9HC52