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FNTA Antikörper (Middle Region)

FNTA Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN357717
  • Target Alle FNTA Antikörper anzeigen
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 50
    • 25
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 48
    • 2
    Kaninchen
    Klonalität
    • 49
    • 1
    Polyklonal
    Konjugat
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FNTA Antikörper ist unkonjugiert
    Applikation
    • 49
    • 22
    • 13
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects FNTA (Center).
    Aufreinigung
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human FNTA.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product FNTA Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blot: 1/100-1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    Andere Bezeichnung
    FNTA (FNTA Produkte)
    Synonyme
    ATFTA antikoerper, FARNESYLTRANSFERASE A antikoerper, FARNESYLTRANSFERASE SUBUNIT A antikoerper, PFT/PGGT-IALPHA antikoerper, PLP antikoerper, PLURIPETALA antikoerper, farnesyltransferase A antikoerper, FPTA antikoerper, PGGT1A antikoerper, PTAR2 antikoerper, PFAS antikoerper, FTA antikoerper, farnesyltransferase A antikoerper, farnesyltransferase, CAAX box, alpha antikoerper, FTA antikoerper, FNTA antikoerper, Fnta antikoerper
    Hintergrund
    FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.Synonyms: CAAX farnesyltransferase subunit alpha, FTase-alpha, GGTase-I-alpha, Protein farnesyltransferase / geranylgeranyltransferase type-1 subunit alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha
    Molekulargewicht
    44408 Da
    Gen-ID
    2339, 9606
    UniProt
    P49354
    Pathways
    Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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