GDF5 Antikörper (N-Term)

Produktnummer ABIN357461

Der Kaninchen Polyklonal Anti-GDF5-Antikörper wurde für WB und EIA validiert. Er ist geeignet, GDF5 in Proben von Human zu detektieren.

Kurzübersicht für GDF5 Antikörper (N-Term) (ABIN357461)

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GDF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-GDF5 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects GDF5 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu GDF5

Target: GDF5 (Growth Differentiation Factor 5 (GDF5))

Andere Bezeichnung: BMP14 / GDF5

Hintergrund: GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.Synonyms: Bone Morphogenetic Protein 14, CDMP1, Cartilage-derived morphogenetic protein 1, GDF-5, Growth/differentiation factor 5, Radotermin

Molekulargewicht: 55410 Da

Gen-ID: 8200, 9606

UniProt: P43026