Growth Differentiation Factor 10 (GDF10) (N-Term) Antikörper

Details zu Produkt Nr. ABIN357454, Anbieter: Anmelden zum Anzeigen
Antigen
  • GDF10
  • BMP-3b
  • BMP3B
  • Bmp3b
  • bmp3b
  • gdf-10
  • xBMP-3b
  • growth differentiation factor 10
  • growth differentiation factor 10 L homeolog
  • GDF10
  • Gdf10
  • gdf10.L
Epitop
N-Term
10
10
10
10
9
7
4
3
3
3
2
2
2
2
1
Reaktivität
Human
84
34
20
2
2
2
1
1
1
1
Wirt
Kaninchen
83
4
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
7
6
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
64
37
26
13
8
7
6
3
3
3
3
2
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GDF10.
Isotyp Ig Fraction
Spezifität Thisa ntibody detects GDF10 at N-term.
Reinigung Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Antigen
Andere Bezeichnung BMP3B / GDF10 (GDF10 Antibody Abstract)
Hintergrund GDF10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.Synonyms: BIP, Bone morphogenetic protein 3b, Bone-inducing protein, GDF-10, Growth/differentiation factor 10
Molekulargewicht 53121 Da
Gen-ID 2662, 9606
UniProt P55107
Applikations-hinweise ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Bilder des Herstellers
 image for anti-Growth Differentiation Factor 10 (GDF10) (N-Term) antibody (ABIN357454) anti-Growth Differentiation Factor 10 (GDF10) (N-Term) antibody
 image for anti-Growth Differentiation Factor 10 (GDF10) (N-Term) antibody (ABIN357454) anti-Growth Differentiation Factor 10 (GDF10) (N-Term) antibody (Image 2)
Allgemeine Veröffentlichungen Ducy, Karsenty: "The family of bone morphogenetic proteins." in: Kidney international, Vol. 57, Issue 6, pp. 2207-14, 2000 (PubMed).

Hino, Takao, Takeshita, Konno, Nishizawa, Matsuo, Kangawa: "cDNA cloning and genomic structure of human bone morphogenetic protein-3B (BMP-3b)." in: Biochemical and biophysical research communications, Vol. 223, Issue 2, pp. 304-10, 1996 (PubMed).

Cunningham, Jenkins, Gilbert, Copeland, Reddi, Lee: "Growth/differentiation factor-10: a new member of the transforming growth factor-beta superfamily related to bone morphogenetic protein-3." in: Growth factors (Chur, Switzerland), Vol. 12, Issue 2, pp. 99-109, 1996 (PubMed).

Haben Sie etwas anderes gesucht?