Neurogenin 1 Antikörper (N-Term)

Produktnummer ABIN357407

Produktdetails anti-Neurogenin 1 Antikörper

Target: Neurogenin 1 (NEUROG1)

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurogenin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects NeuroG1 at N-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NeuroG1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu Neurogenin 1

Target: Neurogenin 1 (NEUROG1)

Andere Bezeichnung: Neurogenin 1 (NEUROG1 Produkte)

Synonyme: ath4c antikoerper, neurogenin-1 antikoerper, ngn1 antikoerper, NEUROG1 antikoerper, aka antikoerper, ngn antikoerper, math4c antikoerper, neurod3 antikoerper, neurogenin antikoerper, neurogenin1 antikoerper, AKA antikoerper, Math4C antikoerper, Neurod3 antikoerper, bHLHa6 antikoerper, NEUROD3 antikoerper, Ngn1 antikoerper, cb260 antikoerper, chunp6899 antikoerper, ngr1 antikoerper, zNgn1 antikoerper, neurogenin 1 antikoerper, NEUROG1 antikoerper, neurog1 antikoerper, Neurog1 antikoerper

Hintergrund: Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.Synonyms: NEUROD3, NGN, NGN1, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, Neurogenin 1

Molekulargewicht: 25717 Da

Gen-ID: 4762

NCBI Accession: NP_006152

UniProt: Q92886