Neurogenin 1 Antikörper (N-Term)
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- Target Alle Neurogenin 1 (NEUROG1) Antikörper anzeigen
- Neurogenin 1 (NEUROG1)
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Neurogenin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Spezifität
- This antibody detects NeuroG1 at N-term.
- Aufreinigung
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Immunogen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human NeuroG1.
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product NEUROG1 Primärantikörper
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- Applikationshinweise
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Target
- Neurogenin 1 (NEUROG1)
- Andere Bezeichnung
- Neurogenin 1 (NEUROG1 Produkte)
- Hintergrund
- Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.Synonyms: NEUROD3, NGN, NGN1, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, Neurogenin 1
- Molekulargewicht
- 25717 Da
- Gen-ID
- 4762
- NCBI Accession
- NP_006152
- UniProt
- Q92886
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