GJA8 Antikörper (C-Term)

Produktnummer ABIN357099

Dieses Anti-GJA8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GJA8 in WB, IHC (p) und EIA. Geeignet für Human und Maus.

Kurzübersicht für GJA8 Antikörper (C-Term) (ABIN357099)

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJA8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GJA8 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Connexin 50 (GJA8) at C-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GJA8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu GJA8

Target: GJA8 (Gap Junction Protein, alpha 8, 50kDa (GJA8))

Andere Bezeichnung: GJA8 / Cx50

Hintergrund: GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.Synonyms: Connexin-50, Gap junction alpha-8 protein, Lens fiber protein MP70

Molekulargewicht: 48097 Da

Gen-ID: 2703, 9606

UniProt: P48165