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GJB6 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-GJB6-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, GJB6 in Proben von Human zu detektieren.
Produktnummer ABIN357095

Kurzübersicht für GJB6 Antikörper (N-Term) (ABIN357095)

Target

Alle GJB6 Antikörper anzeigen
GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Reaktivität

  • 31
  • 11
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 28
  • 2
  • 1
Kaninchen

Klonalität

  • 30
  • 1
Polyklonal

Konjugat

  • 15
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GJB6 Antikörper ist unkonjugiert

Applikation

  • 18
  • 16
  • 15
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 9
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    AA 95-124, N-Term

    Spezifität

    This antibody detects GJB6 at N-term.

    Aufreinigung

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogen

    KLH conjugated synthetic peptide between 95~124 amino acids from the N-terminal region of Human GJB6.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium Azide as preservative

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

    Andere Bezeichnung

    GJB6 / Cx30

    Hintergrund

    Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.Synonyms: Connexin-30, Gap junction beta-6 protein

    Molekulargewicht

    30387 Da

    Gen-ID

    10804, 9606

    UniProt

    O95452

    Pathways

    Sensory Perception of Sound
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