Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Cx40/GJA5 Antikörper (N-Term)

Dieses Anti-Cx40/GJA5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cx40/GJA5 in WB und EIA. Geeignet für Human.
Produktnummer ABIN357093

Kurzübersicht für Cx40/GJA5 Antikörper (N-Term) (ABIN357093)

Target

Alle Cx40/GJA5 (GJA5) Antikörper anzeigen
Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Reaktivität

  • 42
  • 16
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 48
  • 2
Kaninchen

Klonalität

  • 48
  • 2
Polyklonal

Konjugat

  • 31
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cx40/GJA5 Antikörper ist unkonjugiert

Applikation

  • 34
  • 22
  • 22
  • 12
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    This antibody detects Connexin 40 (GJA5) at N-term.

    Aufreinigung

    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GJA5.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target

    Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

    Andere Bezeichnung

    GJA5 / Cx40

    Hintergrund

    Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell closely packed transmembrane channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. Connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 is designated alpha-1 gap junction protein, whereas CX32 and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43. Connexins have four transmembrane, three intracellular, and two extracellular regions. Different tissues express different connexins, though tissue specificities overlap, and a given tissue or cell can express several different connexins. Developmental regulation of at least some of the connexin genes has been found. Embryo implantation is regulated in part by temporally changing patterns of expression of connexins in the embryo and the maternal decidua.Synonyms: Connexin-40, Gap junction alpha-5 protein

    Molekulargewicht

    40249 Da

    Gen-ID

    2702, 9606

    UniProt

    P36382

    Pathways

    Cell-Cell Junction Organization
Sie sind hier:
Chat with us!