P-Cadherin Antikörper (C-Term)

Produktnummer ABIN357039

Dieses Anti-P-Cadherin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von P-Cadherin in WB, IHC (p) und EIA. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für P-Cadherin Antikörper (C-Term) (ABIN357039)

Target: P-Cadherin (CDH3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-P-Cadherin Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects CDH3 at C-term.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CDH3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-P-Cadherin Antikörper (ABIN357039)

Broussard, Kim, Wiley, Marquez, Annis, Pritchard, Disis: "Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions." in: Cancer prevention research (Philadelphia, Pa.), Vol. 6, Issue 7, pp. 666-74, (2013) (PubMed).

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: Cadherin-3

Hintergrund: CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.Synonyms: CDH3, CDHP, Cadherin P, P-Cadherin, Placental cadherin

Molekulargewicht: 91418 Da

Gen-ID: 1001, 9606

UniProt: P22223