YBX2 Antikörper (Middle Region)
Kurzübersicht für YBX2 Antikörper (Middle Region) (ABIN356884)
Target
Alle YBX2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Spezifität
- This antibody detects YBX2 at center.
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Aufreinigung
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Isotyp
- Ig Fraction
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Applikationshinweise
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- YBX2 (Y Box Binding Protein 2 (YBX2))
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Andere Bezeichnung
- YBX2
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Hintergrund
- Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.Synonyms: CSDA3, Contrin, DBPC, DNA-binding protein C, Germ cell-specific Y-box-binding protein, MSY2, MSY2 homolog, Y-box-binding protein 2
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Molekulargewicht
- 38518 Da
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Gen-ID
- 51087, 9606
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UniProt
- Q9Y2T7
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Pathways
- Chromatin Binding
Target
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