SOX9 Antikörper (N-Term)

Produktnummer ABIN356879

Produktdetails anti-SOX9 Antikörper

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects SOX9 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS, then purified by peptide affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SOX9.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry. Immunofluorescence: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9 (SOX9 Produkte)

Synonyme: CMD1 antikoerper, CMPD1 antikoerper, SRA1 antikoerper, LOC100227849 antikoerper, 2010306G03Rik antikoerper, AV220920 antikoerper, mKIAA4243 antikoerper, SOX-9 antikoerper, cmd1 antikoerper, cmpd1 antikoerper, sox-9 antikoerper, sox9 antikoerper, sox9-a antikoerper, sox9-b antikoerper, sox9b antikoerper, sra1 antikoerper, SRY-box 9 antikoerper, transcription factor SOX-9 antikoerper, SRY (sex determining region Y)-box 9 antikoerper, SRY box 9 antikoerper, SRY-box 9 L homeolog antikoerper, SOX9 antikoerper, LOC100227849 antikoerper, Sox9 antikoerper, sox9.L antikoerper

Hintergrund: SOX9 is a member of the family of SOX (Sry-type high mobility group box) genes that were first identified on the basis of region with high homology to that of Sry (Sex determining region Y). SOX9 is a transcription factor with a high mobility group DNA-binding domain that is expressed in all prechondrocytic and chondrocytic cells during embryonic development in a pattern that close parallels that of the gene for type II collagen. SOX9 is important in neural crest formation, and is involved in regulating subsequent epithelial-mesenchymal transition and migration. SOX9 recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.Synonyms: CMD1, CMPD1, SRA1, SRY (sex determining region Y)-box 9, SRY-box 9, Transcription factor SOX-9

Gen-ID: 6662, 9606

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development