Cadherin 8 Antikörper (N-Term)

Produktnummer ABIN356866

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cadherin 8 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für Cadherin 8 Antikörper (N-Term) (ABIN356866)

Target: Cadherin 8 (CDH8)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-Cadherin 8 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is specific to CDH8 (N-term).

Aufreinigung: Protein A Chromatography followed by Peptide Affinity purification.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDH8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-Cadherin 8 Antikörper (ABIN356866)

Kher, Sha, Escobar, Andreoli, Wang, Xu, Wandinger-Ness, Bacallao: "Ectopic expression of cadherin 8 is sufficient to cause cyst formation in a novel 3D collagen matrix renal tubule culture." in: American journal of physiology. Cell physiology, Vol. 301, Issue 1, pp. C99-C105, (2011) (PubMed).

Details zu Cadherin 8

Target: Cadherin 8 (CDH8)

Andere Bezeichnung: Cadherin-8

Hintergrund: CDH8 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.Synonyms: CDH8

Gen-ID: 1006, 9606

UniProt: P55286

Pathways: Cell-Cell Junction Organization