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SETD8 Antikörper (C-Term)
SETD8
Reaktivität: Human
WB, EIA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-SETD8 Antikörper
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Target
Alle SETD8 Antikörper anzeigen
SETD8
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Bindungsspezifität
Alle Epitope für SETD8 Antikörper
AA 364-393, C-Term
Reaktivität
Alle Reaktivitäten für SETD8 Antikörper
Human
Wirt
Alle Wirte für SETD8 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für SETD8 Antikörper
Polyklonal
Konjugat
Alle Konjugate für SETD8 Antikörper
Dieser SETD8 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für SETD8 Antikörper
Western Blotting (WB), Enzyme Immunoassay (EIA)
Spezifität
This antibody is specific to Human SETD8 / SET07 (C-term)
Aufreinigung
Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen
KLH conjugated synthetic peptide between 364~393 amino acids from the C-terminal region of human SET07
Isotyp
Ig Fraction
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Discover our top product SETD8 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1/1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Details zu SETD8
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Target
SETD8
(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
Andere Bezeichnung
SETD8 / SET07 (SETD8 Produkte )
Synonyme
KMT5A antikoerper, PR-Set7 antikoerper, SET07 antikoerper, SET8 antikoerper, 2410195B05Rik antikoerper, AA617402 antikoerper, AW536475 antikoerper, PR-SET7 antikoerper, setd8b antikoerper, wu:fc23f12 antikoerper, zgc:171649 antikoerper, Pr-set7 antikoerper, RGD1305893 antikoerper, Setd8 antikoerper, kmt5a antikoerper, kmt5a-a antikoerper, setd8 antikoerper, setd8-a antikoerper, set8a antikoerper, setd8a antikoerper, wu:fj33f02 antikoerper, zgc:153719 antikoerper, lysine methyltransferase 5A antikoerper, lysine methyltransferase 5Ab antikoerper, lysine methyltransferase 5A S homeolog antikoerper, lysine methyltransferase 5Aa antikoerper, KMT5A antikoerper, Kmt5a antikoerper, kmt5ab antikoerper, kmt5a.S antikoerper, kmt5aa antikoerper
Hintergrund
SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.Synonyms: H4-K20-HMTase SETD8, Histone-lysine N-methyltransferase SETD8, KMT5A, Lysine N-methyltransferase 5A, PR-Set7, PR/SET domain-containing protein 07, PRSET7, SET domain-containing protein 8, SET8
Gen-ID
387893, 9606
UniProt
Q9NQR1
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