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DNMT3A Antikörper (N-Term)

Dieses Anti-DNMT3A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DNMT3A in WB, IHC (p) und EIA. Geeignet für Human.
Produktnummer ABIN356568

Kurzübersicht für DNMT3A Antikörper (N-Term) (ABIN356568)

Target

Alle DNMT3A Antikörper anzeigen
DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reaktivität

  • 130
  • 53
  • 53
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 120
  • 11
Kaninchen

Klonalität

  • 111
  • 20
Polyklonal

Konjugat

  • 56
  • 9
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser DNMT3A Antikörper ist unkonjugiert

Applikation

  • 88
  • 51
  • 32
  • 26
  • 26
  • 21
  • 12
  • 9
  • 9
  • 8
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 16
    • 16
    • 13
    • 8
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    This antibody is specific to Dnmt3a (N-term). It will cross reacts with Mouse (Predicted by 100 % Antigen Homology).

    Aufreinigung

    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Dnmt3a.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10approx. 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

    Andere Bezeichnung

    DNMT3A

    Hintergrund

    CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.Synonyms: DNA (cytosine-5)-methyltransferase 3A, DNA MTase HsaIIIA, DNA methyltransferase HsaIIIA, M.HsaIIIA

    Gen-ID

    1788, 9606

    UniProt

    Q9Y6K1
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