Transferrin Antikörper

Produktnummer ABIN356489

Der Kaninchen Polyklonal anti-Transferrin Antikörper wird verwendet zum Nachweis von Transferrin in Proben von Human. Er wurde validiert für IP und EIA.

Kurzübersicht für Transferrin Antikörper (ABIN356489)

Target: Transferrin (TF)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transferrin Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Produktdetails anti-Transferrin Antikörper

Spezifität: This antibody is specific for Transferrin (TF).

Aufreinigung: Protein A Chromatography.

Immunogen: Purified human transferrin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suitable for use in Immunoprecipitation and ELISA (1/1,000-1/10,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.05 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu Transferrin

Target: Transferrin (TF)

Hintergrund: Transferrin is a blood plasma protein for iron ion delivery. It is a is a glycoprotein, which binds iron very tightly but reversibly. Transferrin has a molecular weight of around 80 kilo Daltons and contains 2 specific high affinity Fe (III) binding sites. It is synthesized in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. The iron is transported in blood and interstitial fluids to sites of use and disposal. Iron/Transferrin is essential in hemoglobin synthesis and for certain types of cell division. Serum concentration rises in iron deficiency and pregnancy and falls in iron overload, infection and inflammatory conditions. When a transferrin protein loaded with iron encounters a transferrin receptor on the surface of a cell (importantly, to erythroid precursors in the bone marrow), it binds to it and is consequently transported into the cell in a vesicle.Synonyms: Beta-1 metal-binding globulin, Serotransferrin, Siderophilin

Gen-ID: 7018

NCBI Accession: NP_001054

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis