ELISA: 1/1,000. Western blotting: 1/100-1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
AML1-EVI-1 antikoerper, EVI1 antikoerper, MDS1 antikoerper, MDS1-EVI1 antikoerper, PRDM3 antikoerper, D630039M04Rik antikoerper, Evi-1 antikoerper, Evi1 antikoerper, Jbo antikoerper, Mds antikoerper, Mds1 antikoerper, Mds1-Evi1 antikoerper, Prdm3 antikoerper, Znfpr1b1 antikoerper, evi1 antikoerper, im:7140716 antikoerper, prdm3 antikoerper, evi-1 antikoerper, mecom antikoerper, mecom-a antikoerper, mecom-b antikoerper, xEvi-1 antikoerper, evi1-B antikoerper, MDS1 and EVI1 complex locus antikoerper, MDS1 and EVI1 complex locus L homeolog antikoerper, MDS1 and EVI1 complex locus S homeolog antikoerper, MECOM antikoerper, Mecom antikoerper, mecom antikoerper, mecom.L antikoerper, mecom.S antikoerper
Hintergrund
Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. MDS1, first identified as part of a fusion transcript resulting from the t(3,21)(q26,q22), encodes a small protein of unknown function. EVI1 encodes a zinc finger protein inappropriately overexpressed by chromosomal rearrangements. EVI1 and MDS1 are unusual in that they can either encode separate proteins, or they can be expressed as a fusion protein MDS1/EVI1. EVI1 and MDS1/EVI1 have opposite functions as transcription factors.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1