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SUV39H1 Antikörper (N-Term)

SUV39H1 Reaktivität: Human, Maus WB, EIA Wirt: Maus Monoclonal 42AT239-96-72 unconjugated
Produktnummer ABIN356373
  • Target Alle SUV39H1 Antikörper anzeigen
    SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
    Bindungsspezifität
    • 22
    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 66
    • 17
    • 7
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 59
    • 7
    Maus
    Klonalität
    • 59
    • 7
    Monoklonal
    Konjugat
    • 23
    • 8
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SUV39H1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 40
    • 17
    • 13
    • 13
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific to SUV39H1.
    Produktmerkmale
    Synonyms: SUV39H, Lysine N-methyltransferase 1A, Histone-lysine N-methyltransferase SUV39H1,Histone H3-K9 methyltransferase 1, Position-effect variegation 3-9 homolog, Suppressor ofvariegation 3-9 homolog 1
    Aufreinigung
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody was raised using purified recombinant GST fusion protein encodingN-terminal of human SUV39H1.
    Klon
    42AT239-96-72
    Isotyp
    IgG1
    Top Product
    Discover our top product SUV39H1 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100-1/500.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))
    Andere Bezeichnung
    SUV39H1 / KMT1A (SUV39H1 Produkte)
    Synonyme
    H3-K9-HMTase 1 antikoerper, KMT1A antikoerper, MG44 antikoerper, SUV39H antikoerper, AI852103 antikoerper, AL022883 antikoerper, DXHXS7466e antikoerper, mIS6 antikoerper, RGD1565028 antikoerper, kmt1a antikoerper, suv39h antikoerper, fe02c04 antikoerper, suv39h1 antikoerper, wu:fe02c04 antikoerper, zgc:101027 antikoerper, fe47h06 antikoerper, wu:fb18a10 antikoerper, wu:fe47h06 antikoerper, zgc:136593 antikoerper, suppressor of variegation 3-9 homolog 1 antikoerper, suppressor of variegation 3-9 homolog 1 (Drosophila) antikoerper, suppressor of variegation 3-9 homolog 1 L homeolog antikoerper, suppressor of variegation 3-9 homolog 1a antikoerper, suppressor of variegation 3-9 homolog 1b antikoerper, SUV39H1 antikoerper, Suv39h1 antikoerper, suv39h1.L antikoerper, suv39h1a antikoerper, suv39h1b antikoerper
    Hintergrund
    Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.Synonyms: Histone H3-K9 methyltransferase 1, Histone-lysine N-methyltransferase SUV39H1, Lysine N-methyltransferase 1A, Position-effect variegation 3-9 homolog, SUV39H, Suppressor of variegation 3-9 homolog 1
    Gen-ID
    6839
    UniProt
    O43463
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