DEFA5 Antikörper (cleaved)

Produktnummer ABIN356090

Der Maus Monoklonal Anti-DEFA5-Antikörper wurde für IHC validiert. Er ist geeignet, DEFA5 in Proben von Human zu detektieren.

Kurzübersicht für DEFA5 Antikörper (cleaved) (ABIN356090)

Target: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DEFA5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: 8C8

Produktdetails anti-DEFA5 Antikörper

Bindungsspezifität: cleaved

Kreuzreaktivität: Human

Aufreinigung: Aff - Purified

Immunogen: Full-length proHD5 protein. [Swiss-Prot# Q01523] The propeptide is the full-length protein. In the mature form, it is cleaved at residue 63 (alanine).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Details zu DEFA5

Target: DEFA5 (Defensin, alpha 5, Paneth Cell-Specific (DEFA5))

Andere Bezeichnung: Defensin 5

Hintergrund: Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. Alpha-defensins 5 and 6 probably contribute to innate defense of the GI mucosal surface by protecting against microbial invasion in states of intestinal inflammation.

UniProt: Q01523