VPS29 Antikörper (C-Term)

Produktnummer ABIN351326

Produktdetails anti-VPS29 Antikörper

Target: VPS29 (Vacuolar Protein Sorting 29 (VPS29))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS29 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Rabbit antibody to VPS29

Spezifität: Specific for VPS29.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from the c-terminal region of mouse VPS29 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat human chicken zebra fish and xenopus.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu VPS29

Target: VPS29 (Vacuolar Protein Sorting 29 (VPS29))

Andere Bezeichnung: VPS29 (VPS29 Produkte)

Hintergrund: FUNCTION: Essential component of the retromer complex a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro). Has no activity towards p-nitrophenylphosphate p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). CATALYTIC ACTIVITY: O-phospho-L(or D)-serine + H2O = L(or D)-serine + phosphate. COFACTOR: Binds 2 zinc ions per subunit. SUBCELLULAR LOCATION: Cytoplasm. Membrane, Peripheral membrane protein. Endosome membrane, Peripheral membrane protein.

UniProt: Q9QZ88