Trpl Antikörper (4th Cytoplasmic Loop)

Produktnummer ABIN351177

Dieses Anti-Trpl-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Trpl in IHC und WB. Geeignet für Drosophila melanogaster.

Kurzübersicht für Trpl Antikörper (4th Cytoplasmic Loop) (ABIN351177)

Target: Trpl (Transient Receptor Potential-Like (Trpl))

Reaktivität: Drosophila melanogaster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Trpl Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-Trpl Antikörper

Bindungsspezifität: 4th Cytoplasmic Loop

Verwendungszweck: Rabbit antibody to drosophila TRPL

Spezifität: Specific for TRPL.

Kreuzreaktivität: Drosophila melanogaster

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from 4th cytoplasmic loop of drosophila TRPL (Transient receptor potential like protein) conjugated to an immunogenic carrier protein was used as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu Trpl

Target: Trpl (Transient Receptor Potential-Like (Trpl))

Andere Bezeichnung: TRPL

Hintergrund: FUNCTION: A light-sensitive calcium channel that is required for inositide-mediated Ca(2+) entry in the retina during phospholipase C (PLC)-mediated phototransduction. Required for vision in the dark and in dim light. Binds calmodulin. Trp and trpl act together in the light response although it is unclear whether as heteromultimers or distinct units. Also forms a functional cation channel with trp-gamma. Activated by fatty acids metabolic stress inositols and GTP-binding proteins. SUBUNIT: Forms heteromultimers with trp-gamma and to a lower extent with trp. Interacts with FKBP59 in vivo and is found in the inaD signaling complex. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. Note: In the dark there is 20 fold more rhabdomeral trpl protein forming plasma membrane channels than in the light. In the light the protein translocates to an intracellular compartment. Protein levels remain unchanged in light and dark conditions.

UniProt: P48994

Pathways: Sensory Perception of Sound, Phototransduction