LIMK2 Antikörper (Internal Region)

Produktnummer ABIN350436

Dieses Anti-LIMK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LIMK2 in WB und IHC. Geeignet für Human.

Kurzübersicht für LIMK2 Antikörper (Internal Region) (ABIN350436)

Target: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIMK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-LIMK2 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit antibody to LIMK2

Spezifität: Specific for LIMK2.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from the internal part of human LIMK2 (LIM domain kinase 2 LIMK-2) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat mouse.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu LIMK2

Target: LIMK2 (LIM Domain Kinase 2 (LIMK2))

Andere Bezeichnung: LIMK2

Hintergrund: FUNCTION: Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro. CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note: Isoform LIMK2a is distributed in the cytoplasm and the nucleus and isoform LIMK2b occurs mainly in the cytoplasm and is scarcely translocated to the nucleus. TISSUE SPECIFICITY: Highest expression in the placenta, moderate level in liver lung kidney and pancreas. LIMK2a is found to be more abundant then LIMK2b in liver colon stomach and spleen while in brain kidney and placenta LIMK2b is the dominant form. In adult lung both LIMK2a and LIMK2b is nearly equally observed.

UniProt: P53671