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COPD (AA 150-200) Antikörper

Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN350257
  • Target
    COPD
    Bindungsspezifität
    • 1
    • 1
    AA 150-200
    Reaktivität
    Human
    Wirt
    • 3
    Kaninchen
    Klonalität
    • 3
    Polyklonal
    Konjugat
    • 3
    Unkonjugiert
    Applikation
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Rabbit antibody to COPD (150-200)
    Spezifität
    Specific for COPD.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from AA 150-200 of human COPD conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat mouse and xenopus.
    Isotyp
    IgG
  • Applikationshinweise
    IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    COPD
    Hintergrund
    FUNCTION: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles which further mediate biosynthetic protein transport from the ER via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs) which are small GTP-binding proteins, the complex also influences the Golgi structural integrity as well as the processing activity and endocytic recycling of LDL receptors. SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus membrane, Peripheral membrane protein, Cytoplasmic side. Cytoplasmic vesicle COPI-coated vesicle membrane, Peripheral membrane protein, Cytoplasmic side. Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi as well as on the vesicles/buds originating from it.
    UniProt
    P48444
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