Cofilin Antikörper
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- Target Alle Cofilin (CFL1) Antikörper anzeigen
- Cofilin (CFL1) (Cofilin 1 (CFL1))
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Reaktivität
- Human
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Wirt
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Schaf
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cofilin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- Specific for Cofilin-1.
- Kreuzreaktivität
- Human, Maus, Ratte
- Kreuzreaktivität (Details)
- Other species not yet tested.
- Aufreinigung
- IgG
- Immunogen
- A synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat, mouse and monkey.
- Isotyp
- IgG
- Top Product
- Discover our top product CFL1 Primärantikörper
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- Applikationshinweise
- IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. This antibody may also recognice the unphosphorylated form. Not tested in other applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
- Handhabung
- Avoid freeze and thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Cofilin (CFL1) (Cofilin 1 (CFL1))
- Andere Bezeichnung
- Cofilin-1 (CFL1 Produkte)
- Hintergrund
- FUNCTION: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. SUBCELLULAR LOCATION: Nucleus matrix. Cytoplasm, cytoskeleton. Note: Almost completely in nucleus in cells exposed to heat shock or 10 % dimethyl sulfoxide. TISSUE SPECIFICITY: Widely distributed in various tissues.,Growth & Development,Cofilin, non-muscle isoform
- UniProt
- P23528
- Pathways
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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