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Cofilin Antikörper

CFL1 Reaktivität: Human WB, IHC Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN350240
  • Target Alle Cofilin (CFL1) Antikörper anzeigen
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Reaktivität
    • 131
    • 93
    • 90
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 137
    • 9
    • 1
    Schaf
    Klonalität
    • 136
    • 10
    Polyklonal
    Konjugat
    • 70
    • 10
    • 10
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cofilin Antikörper ist unkonjugiert
    Applikation
    • 70
    • 61
    • 43
    • 42
    • 41
    • 41
    • 30
    • 26
    • 16
    • 12
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for Cofilin-1.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from the phospho Y140 & S156 of human Cofilin-1 (Cofilin, non-muscle isoform) conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat, mouse and monkey.
    Isotyp
    IgG
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  • Applikationshinweise
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. This antibody may also recognice the unphosphorylated form. Not tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    Andere Bezeichnung
    Cofilin-1 (CFL1 Produkte)
    Hintergrund
    FUNCTION: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. SUBCELLULAR LOCATION: Nucleus matrix. Cytoplasm, cytoskeleton. Note: Almost completely in nucleus in cells exposed to heat shock or 10 % dimethyl sulfoxide. TISSUE SPECIFICITY: Widely distributed in various tissues.,Growth & Development,Cofilin, non-muscle isoform
    UniProt
    P23528
    Pathways
    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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