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CHMP6 Antikörper (C-Term)

CHMP6 Reaktivität: Maus WB, IHC Wirt: Schaf Polyclonal unconjugated
Produktnummer ABIN350233
  • Target Alle CHMP6 Antikörper anzeigen
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Bindungsspezifität
    • 9
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 24
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 26
    • 1
    Schaf
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    Dieser CHMP6 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 15
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Verwendungszweck
    Sheep antibody to CHMP6
    Spezifität
    Specific for CHMP6.
    Kreuzreaktivität
    Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from the c-terminal region of mouse CHMP6 conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 95% identity with rat's.
    Isotyp
    IgG
    Top Product
    Discover our top product CHMP6 Primärantikörper
  • Applikationshinweise
    IHC WB. Use at a concentration of 10-50,micro,g,ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
    Andere Bezeichnung
    CHMP6 (CHMP6 Produkte)
    Hintergrund
    FUNCTION: Component of the ESCRT-III complex which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex it probably serves as an acceptor for ESCRT-II complex on endosomal membranes. SUBUNIT: Component of the endosomal sorting required for transport complex III (ESCRT-III) at least composed of CHMP1A CHMP1B CHMP2A CHMP2B CHMP3/VPS24 CHMP4A/SHAX2 CHMP4B/SHAX1 CHMP4C/SHAX3 CHMP5/SNF7DC2 and CHMP6/VPS20. In the complex it interacts directly with CHMP4A CHMP4B and CHMP4C. Interacts directly with SNF8 VPS25 and VPS36 components of the ESCRT-II complex. SUBCELLULAR LOCATION: Intracytoplasmic membrane. Endosome membrane, Lipid-anchor . Note: Localizes to endosomal membranes.
    UniProt
    P0C0A3
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