CHMP3 Antikörper (N-Term)
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- Target Alle CHMP3 Antikörper anzeigen
- CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
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Schaf
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHMP3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Verwendungszweck
- Sheep antibody to CHMP3
- Spezifität
- Specific for CHMP3.
- Kreuzreaktivität
- Human, Maus, Ratte
- Kreuzreaktivität (Details)
- Other species not yet tested.
- Aufreinigung
- IgG
- Immunogen
- A synthetic peptide from the n-terminal of human CHMP3 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in rat and mouse.
- Isotyp
- IgG
- Top Product
- Discover our top product CHMP3 Primärantikörper
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- Applikationshinweise
- IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.
- Handhabung
- Avoid freeze and thaw cycles.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))
- Andere Bezeichnung
- CHMP3 (CHMP3 Produkte)
- Hintergrund
- FUNCTION: Component of the ESCRT-III complex which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. Required for sorting/trafficking of EGF receptor. In case of infection the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins. SUBCELLULAR LOCATION: Cytoplasm cytosol. Membrane, Lipid-anchor. TISSUE SPECIFICITY: Widely expressed. Expressed in heart brain placenta lung liver skeletal muscle kidney and pancreas.
- UniProt
- Q9Y3E7
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