ACCN1 Antikörper (AA 470-503)

Produktnummer ABIN350042

Der Kaninchen Polyklonal Anti-ACCN1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ACCN1 in Proben von Human zu detektieren.

Kurzübersicht für ACCN1 Antikörper (AA 470-503) (ABIN350042)

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACCN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ACCN1 Antikörper

Bindungsspezifität: AA 470-503

Verwendungszweck: Rabbit antibody to ASIC2 (470-503)

Spezifität: Specific for ASIC2.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from AA 470-503 of human ASIC2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC WB. A concentration of 10-50,micro,g,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu ACCN1

Target: ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Andere Bezeichnung: ASIC2

Hintergrund: FUNCTION: Cation channel with high affinity for sodium which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. SUBUNIT: Homotetramer or heterotetramer with other ASIC proteins. Interacts with STOM. Interacts with PRKCABP and ACCN3. SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein. Note: Localized at the plasma membrane of neurons in the soma and punctated peripheral processes.

UniProt: Q16515

Pathways: Sensory Perception of Sound