PLCz1 Antikörper (Internal Region)

Produktnummer ABIN347397

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLCz1 in ELISA, WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für PLCz1 Antikörper (Internal Region) (ABIN347397)

Target: PLCz1 (Phospholipase C zeta 1 (PLCz1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLCz1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Produktdetails anti-PLCz1 Antikörper

Bindungsspezifität: Internal Region

Spezifität: Reacts with human PLC zeta protein

Kreuzreaktivität (Details): No cross reaction

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from internal part of PLC-zeta-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:100 - 1:1000) ICC(1:50 - 1:1000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Referenzen für anti-PLCz1 Antikörper (ABIN347397)

Janghorban-Laricheh, Ghazavi-Khorasgani, Tavalaee, Zohrabi, Abbasi, Nasr-Esfahani: "An association between sperm PLCζ levels and varicocele?" in: Journal of assisted reproduction and genetics, (2016) (PubMed).

Kamali-Dolat Abadi, Tavalaee, Shahverdi, Nasr-Esfahani: "Evaluation of PLCζ and PAWP Expression in Globozoospermic Individuals." in: Cell journal, Vol. 18, Issue 3, pp. 438-45, (2016) (PubMed).

Details zu PLCz1

Target: PLCz1 (Phospholipase C zeta 1 (PLCz1))

Andere Bezeichnung: Phospholipase C zeta Isoform (PLC-zeta-1)

Hintergrund: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion.

Gen-ID: 89869

UniProt: Q86YW0