alpha Actinin 4 Antikörper (N-Term)

Produktnummer ABIN347113

Der Kaninchen Polyklonal Anti-alpha Actinin 4-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, alpha Actinin 4 in Proben von Human zu detektieren.

Kurzübersicht für alpha Actinin 4 Antikörper (N-Term) (ABIN347113)

Target: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Actinin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-alpha Actinin 4 Antikörper

Bindungsspezifität: N-Term

Spezifität: Reacts with human 110 kDa of ACTN4 protein

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reacts with rat and mouse protein due to sequence homology.

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from N- term domain of the human ACTN4 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/100 to 1/500 - WB : 1/500 to 1/2 000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu alpha Actinin 4

Target: alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

Andere Bezeichnung: alpha-Actinin-4 (ACTN4)

Hintergrund: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions.

Gen-ID: 81

UniProt: O43707

Pathways: Proton Transport