AGR3 Antikörper

Produktnummer ABIN343711

Dieses Maus Monoklonal-Antikörper erkennt spezifisch AGR3 in WB, IHC (p), IHC (fro) und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für AGR3 Antikörper (ABIN343711)

Target: AGR3 (Anterior Gradient 3 (AGR3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AGR3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Klon: AGR3-1

Produktdetails anti-AGR3 Antikörper

Verwendungszweck: Anti-AGR3 Purified

Spezifität: The antibody AGR3.1 recognizes the epitope HETTDKNLS within the AGR3 (AG3) protein (19-20 kDa), a secreted cytoplasmic protein which can serve as a marker of carcinogenesis.

Kreuzreaktivität (Details): Human, Other species Not tested

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Purified human AGR3 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (paraffin sections): Recommended dilution: 1 μg/mL, positive tissue: breast cancer.
Immunohistochemistry (frozen sections): Recommended dilution: 1 μg/mL, positive tissue: breast cancer.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu AGR3

Target: AGR3 (Anterior Gradient 3 (AGR3))

Andere Bezeichnung: AGR3

Hintergrund: Anterior gradient 3, protein disulphide isomerase,AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.,AG3, HAG3

Gen-ID: 155465

UniProt: Q8TD06