MTA2 Antikörper (AA 652-668)

Produktnummer ABIN342361

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MTA2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für MTA2 Antikörper (AA 652-668) (ABIN342361)

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MTA2 Antikörper

Bindungsspezifität: AA 652-668

Spezifität: Recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. Does not cross-react with MTA1.

Aufreinigung: Immunoaffinity purified

Immunogen: Peptide corresponding to aa 652-668 of human PID/MTA2. This sequence differs from that of mouse by one amino acid.

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.5 - 1 μg/mL)

Usage: Western Blot: A band of 75 kD is detected.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu MTA2

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Andere Bezeichnung: MTA2

Hintergrund: Name/Gene ID: MTA2

Synonyms: MTA2, Metastasis-associated 1-like 1, MTA1L1, PID, MTA1-L1, MTA1-L1 protein

Gen-ID: 9219

UniProt: O94776

Pathways: Chromatin Binding