MTBP Antikörper (AA 122-139)
Kurzübersicht für MTBP Antikörper (AA 122-139) (ABIN342358)
Target
Alle MTBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 122-139
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Spezifität
- Recognizes human and mouse MTBP which is involved in the p53 network of tumor suppression. p53 transcriptionally activates the MDM2 gene, then the translated MDM2 protein binds to p53 and promotes degradation of p53. MTBP binds to MDM2 and inhibits the modulating effect of MDM2 on p53. MTBP is expressed in a variety of normal tissues.
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Aufreinigung
- Immunoaffinity purified
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Immunogen
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Peptide corresponding to aa 122-139 of human MTBP. This sequence differs from that of mouse by three amino acids.
Type of Immunogen: Synthetic peptide
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Applikationshinweise
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Approved: WB (0.5 - 1 μg/mL)
Usage: Western Blot: A band of 104 kD is detected. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- MTBP (MDM2 Binding Protein (MTBP))
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Andere Bezeichnung
- MTBP
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Hintergrund
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Name/Gene ID: MTBP
Synonyms: MTBP, Mdm2-binding protein, MDM2BP, HMTBP -
Gen-ID
- 27085
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UniProt
- Q96DY7
Target
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