Estrogen Receptor alpha Antikörper (N-Term)
Kurzübersicht für Estrogen Receptor alpha Antikörper (N-Term) (ABIN342250)
Target
Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Recognizes human ER-a, a 65 kD protein and a member of the steroid family of nuclear receptors. ER-a is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, ER-a can positively or negatively regulate gene transcription.
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Aufreinigung
- Protein G purified
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Immunogen
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6-His fusion protein containing the region encoding aa 1-190 of human estrogen receptor-a (ER-a) expressed in E. coli.
Type of Immunogen: Fusion protein -
Isotyp
- IgG1
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Applikationshinweise
- Approved: IP (1 - 5 μg/mL), WB
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Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, pH 7.4
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Handhabung
- Avoid freeze/thaw cycles.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -70°C, avoid freeze/thaw cycles.
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Andere Bezeichnung
- ER Alpha / Estrogen Receptor
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Hintergrund
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Name/Gene ID: ESR1
Subfamily: NR3 Steroid receptor
Family: NHR
Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha -
Gen-ID
- 2099
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UniProt
- P03372
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Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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