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Tyrosine Hydroxylase Antikörper (pSer40)

Der Kaninchen Polyklonal anti-Tyrosine Hydroxylase Antikörper (ABIN337188) detektiert spezifisch Tyrosine Hydroxylase in WB, IHC, IF, IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.
Produktnummer ABIN337188
610,95 €
Zzgl. Versandkosten 20,00 € und MwSt
50 μL
Lieferung nach: Deutschland
Lieferung in 15 bis 20 Werktagen

Kurzübersicht für Tyrosine Hydroxylase Antikörper (pSer40) (ABIN337188)

Target

Alle Tyrosine Hydroxylase (TH) Antikörper anzeigen
Tyrosine Hydroxylase (TH)

Reaktivität

  • 147
  • 140
  • 116
  • 11
  • 9
  • 9
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 143
  • 36
  • 6
  • 5
  • 2
Kaninchen

Klonalität

  • 125
  • 67
Polyklonal

Konjugat

  • 119
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Tyrosine Hydroxylase Antikörper ist unkonjugiert

Applikation

  • 141
  • 104
  • 63
  • 55
  • 35
  • 27
  • 24
  • 22
  • 16
  • 14
  • 13
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 20
    • 15
    • 14
    • 12
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer40

    Spezifität

    Specific for the ~60k tyrosine hydroxylase protein phosphorylated at Ser40. Some higher molecular weight bands may be detected by the antibody depending upon the brain region being studied, protein loads and the detection methods used. The antibody has three orders of magnitude selectivity over dephospho TH.

    Aufreinigung

    Immunoaffinity purified

    Immunogen

    Phosphopeptide corresponding to amino acid residues surrounding the phosphoSer40 of rat tyrosine hydroxylase.
  • Applikationshinweise

    Approved: IF (1:1000), IHC, IHC-Fr (1:1000), IHC-P (5 μg/mL), WB (1:1000)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

    Kommentare

    Target Species of Antibody: Rat

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Short term: -20°C
    Long term: -80°C.
  • Target

    Tyrosine Hydroxylase (TH)

    Andere Bezeichnung

    TH / Tyrosine Hydroxylase

    Hintergrund

    Name/Gene ID: TH
    Family: Monooxygenase

    Synonyms: TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase

    Gen-ID

    7054

    UniProt

    P07101

    Pathways

    Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour
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