hCG Antikörper

Produktnummer ABIN336855

Der Maus Monoklonal anti-hCG Antikörper (Klon hCG 205) (ABIN336855) detektiert spezifisch hCG in IHC und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für hCG Antikörper (ABIN336855)

Target: hCG (Chorionic Gonadotropin (hCG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser hCG Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: HCG 205

Produktdetails anti-hCG Antikörper

Spezifität: Molecular Weight: 22 kDa.

Immunogen: Purified beta hCG

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears. For IHC dilute conc. antibodies 1:50-1:100, use streptavidin-biotin system or polymer system, incubate 30 minutes at room temperature. Prediluted antibody is ready to be used for IHC. Antigen retriever like citrate enhances the staining of FFPE tissue sections (Boil tissue in 10 mM citrate, pH 6.0 for 10-15 minutes followed by cooling for 10-15 minutes at RT. The optimum dilution should be determined by the individual lab. Positive Control: Human placenta, choriocarcinoma. Cellular Localization: Cytoplasmic.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The concentrated antibodies are supplied in PBS with 1% BSA, 0.05% azide, pH 7.4. The Prediluted antibody is supplied in our Universal antibody dilution buffer (AR-6526) green in color.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu hCG

Target: hCG (Chorionic Gonadotropin (hCG))

Andere Bezeichnung: Chorionic Gonadotropin

Substanzklasse: Hormone

Hintergrund: Human chorionic gonadotropin (hCG) is a oligosaccharide glycopeptide hormone (244 aa) produced in pregnancy that is made by the embryo soon after conception and later by the syncytiotrophoblast (part of the placenta). Its role is to prevent the disintegration of the corpus luteum of the ovary and thereby maintain progesterone production that is critical for a pregnancy in humans. hCG may have additional functions, for instance, it is thought that hCG affects the immune tolerance of the pregnancy. Early pregnancy testing, in general, is based on the detection or measurement of hCG. HCG is compose of two non-identical, non-covalently linked polypeptide chains as alpha and beta-subunits. The alpha subunit of hCG is nearly identical to that of thyroid stimulating (TSH), FSH, and LH.A germ cell tumor which is + for Cytokeratin, PLAP, and hCG but negative for EMA and alpha feto protein is probably choriocarcinoma