AVEN Antikörper (AA 254-362)
Kurzübersicht für AVEN Antikörper (AA 254-362) (ABIN336088)
Target
Alle AVEN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 254-362
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Spezifität
- The antibody recognizes AVEN / PDCD12.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
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Produktmerkmale
- Synonyms: PDCD12, Cell death regulator Aven, Programmed cell death 12
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Aufreinigung
- Protein-G affinity chromatography
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Immunogen
- Recombinant human PDCD12 (aa 254-362) purified from E. coli
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA. Western blot (1: 1,000 - 1: 3,000). Immunohistochemistry on paraffin sections (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
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Andere Bezeichnung
- AVEN
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Hintergrund
- PDCD12 (Programmed cell death 12), also referred to as AVEN, represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein that blocks apoptosis impeded by Apaf-1 mediated caspase activation. Bcl-2 and BAD also interact with PDCD12 to prevent apoptosis. It is expressed in a wide variety of normal tissues including heart, skeletal muscle, kidney, liver, testis, and diseases such as cancer.Synonyms: Cell death regulator Aven, PDCD12, Programmed cell death 12
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Gen-ID
- 57099
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UniProt
- Q9NQS1
Target
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