Laminin Antikörper

Produktnummer ABIN335387

Der Ratte Monoklonal Anti-Laminin-Antikörper wurde für IHC, IHC (fro) und ICC validiert. Er ist geeignet, Laminin in Proben von Human und Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Laminin Antikörper (ABIN335387)

Target: Laminin (LN)

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Laminin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Klon: A5

Produktdetails anti-Laminin Antikörper

Spezifität: Human and mouse.

Aufreinigung: Purified

Immunogen: A5 is a rat monoclonal IgG2a antibody derived by fusion of mouse myeloma cells with spleen cells from a Fisher rat immunized with a laminin preparation from the EHS mouse tumor.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: A5 reacts with laminin. APPLICATIONS A5 is suitable for immunocytochemistry and immunohistochemistry on frozen tissues. Optimal antibody dilution should be determined by titration, recommended range is 1:25 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Referenzen für anti-Laminin Antikörper (ABIN335387)

Ljubimova, Lakhter, Loksh, Yong, Riedinger, Miner, Sorokin, Ljubimov, Black: "Overexpression of alpha4 chain-containing laminins in human glial tumors identified by gene microarray analysis." in: Cancer research, Vol. 61, Issue 14, pp. 5601-10, (2001) (PubMed).

Ljubimov, Bartek, Couchman, Kapuller, Veselov, Kovarik, Perevoshchikov, Krutovskikh: "Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies." in: International journal of cancer. Journal international du cancer, Vol. 50, Issue 4, pp. 562-6, (1992) (PubMed).

Details zu Laminin

Target: Laminin (LN)

Andere Bezeichnung: Laminin

Hintergrund: Basement membrane components play an important role in cell adhesion, locomotion, differentiation and embryonic compartmentalization. Laminin anchors cells to the basement membrane through interactions with integrins at the cell surface and collagens in the basement membrane.