SNCA Antikörper (AA 1-15)

Produktnummer ABIN334636

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SNCA in WB, ELISA und IL. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SNCA Antikörper (AA 1-15) (ABIN334636)

Target: SNCA (Synuclein, alpha (SNCA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNCA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunolocalization (IL)

Produktdetails anti-SNCA Antikörper

Bindungsspezifität: AA 1-15

Verwendungszweck: Anti-SNCA | Alpha-synuclein

Kreuzreaktivität (Details): Human

Homologie: Primates,Chimpanzee,Gorilla

Aufreinigung: Serum

Immunogen: recombinant

Anwendungsinformationen

Applikationshinweise: 1 : 3000 (ELISA), 1-2 μg/mL (IL), 1 : 1000 (WB)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 100 μL of sterile water

Buffer: Serum

Handhabung: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Lagerung: -20 °C

Informationen zur Lagerung: Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Details zu SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Andere Bezeichnung: SNCA

Hintergrund:

Background: Alpha-synuclein is normally an unstructured soluble protein that can aggregate to form insoluble fibrils in pathological conditions characterized by Lewy bodies, such as Parkinson's disease, dementia with Lewy-bodies, and multiple system atrophy.

Additional information: Immunolocalization: human tissue was paraffin-embedded and sectioned. De-waxed and rehydrated in an ethanol gradient. Antigens were retrieved in sodium citrate buffer ( pH 6) at 95 °C for 1 h. The tissue sections were separately incubated for 1 h at RT with primary antibody and antibody binding was visualized with IgG Preoxidase Reagent Kit.This antibody will recognize human SNCA monomers and multimers in Western blot and can be used to detect fibrills in a sandwich ELISA. In ELISA this antibody can be used for detection, combined with AS13 2719 as a capture antibody.

Molekulargewicht: 14 kDa

Gen-ID: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity