BACE1 Antikörper
Kurzübersicht für BACE1 Antikörper (ABIN325261)
Target
Alle BACE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Recognizes human BACE-1 ectodomain. Species cross-reactivity: Mouse.
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Aufreinigung
- Protein G purified
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Immunogen
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NS0-derived rhBACE-1 ectodomain.
Type of Immunogen: Recombinant protein -
Isotyp
- IgG1
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anti-Beta-secretase 1 (BACE1) (AA 22-501) antibody
BACE1 Reaktivität: Human WB, ELISA, IHC (p), PLA Wirt: Maus Monoclonal 2C1 unconjugated
anti-Beta-secretase 1 (BACE1) (AA 112-324) antibodyBACE1 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 3C1C3 unconjugated
anti-Beta-secretase 1 (BACE1) (N-Term) antibodyBACE1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 22-322) antibodyBACE1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 401-501) antibodyBACE1 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 38-70), (N-Term) antibodyBACE1 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB16874 unconjugated
anti-Beta-secretase 1 (BACE1) (AA 46-155) antibodyBACE1 Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (AA 72-121) antibodyBACE1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Affe, Schwein, Fledermaus, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) (C-Term) antibodyBACE1 Reaktivität: Human, Affe IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Beta-secretase 1 (BACE1) antibodyKD Validated BACE1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB4865 unconjugated Recombinant Antibody
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Applikationshinweise
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Approved: ELISA, IP, Neut, WB
Usage: Suitable for use in ELISA, Immunoprecipitation/ Western Blot and Neutralization. The enzyme was then assayed with a peptide substrate. 50 % of the proteolytic activity was inhibited by the antibody at 10 μg/mL (IC50) under conditions in which the enzyme was present at 10 μg/mL and the substrate concentration was 10uM. Considering the molecular masses of the enzyme (75kD) and the antibody (150kD), IC50 was achieved at ~0.5:1 Molar ratio of the antibody to the enzyme. Did not inhibit rhCathepsin D activity under the same conditions. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Sterile PBS
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Konzentration
- Lot specific
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Buffer
- Lyophilized, PBS, pH 7.4, 5 % trehalose
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Andere Bezeichnung
- BACE1 / BACE
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Hintergrund
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Name/Gene ID: BACE1
Subfamily: Aspartic A1
Family: Protease
Synonyms: BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2 -
Gen-ID
- 23621
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UniProt
- P56817
Target
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