MUC1 Antikörper

Produktnummer ABIN3222739

Dieser Maus Monoklonal Antikörper detektiert spezifisch MUC1 in IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MUC1 Antikörper (ABIN3222739)

Target: MUC1 (Mucin 1 (MUC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MUC1 Antikörper

Spezifität: Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).

Produktmerkmale: Host: Hybridization of P3X63-Ag8.653, myeloma cells with spleen cells from Balb/c mice.

Aufreinigung: Purified by Protein A chromatography

Reinheit: > 98 % pure

Immunogen: Human breast cancer cell line ZR 75-1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Capture or detection antibody in serological assays for the research of antigen MUC-1. Forms a suitable pair withX108 , Catalog # L1C00802. Immunohistochemistry on frozen or paraffin sections for the detection of MUC-1. Immunochemical detection of MUC-1 protein.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1:1000~5000

Buffer: 150mM NaCl 10mM Tris, pH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu MUC1

Target: MUC1 (Mucin 1 (MUC1))

Andere Bezeichnung: CA15-3

Hintergrund: Monoclonal Antibody to Carbohydrate Antigen 15-3(CA15-3) (Breast Cancer)

Pathways: Negative Regulation of intrinsic apoptotic Signaling