Lipase A Antikörper
Kurzübersicht für Lipase A Antikörper (ABIN3210008)
Target
Alle Lipase A (LIPA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Purified antibody.
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Immunogen
- LAL antibody was raised in Mouse using a purified recombinant fragment of LAL expressed in E. coli as the immunogen.
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Isotyp
- IgG2a
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Applikationshinweise
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ELISA: 1:10,000, WB: 1:500-1:2000,
Optimal conditions should be determined by the investigator. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- Lot specific
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Buffer
- Purified antibody supplied in PBS containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
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Andere Bezeichnung
- LAL
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Hintergrund
- LAL functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries. Synonyms: Monoclonal LAL antibody, Anti-LAL antibody, Lysosomal acid lipase antibody.
Target
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