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NCR1 Antikörper

Dieses Anti-NCR1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NCR1 in WB, FACS, IF und Func. Geeignet für Rind (Kuh).
Produktnummer ABIN320238

Kurzübersicht für NCR1 Antikörper (ABIN320238)

Target

Alle NCR1 Antikörper anzeigen
NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität

  • 83
  • 64
  • 20
  • 8
  • 5
  • 3
  • 3
Rind (Kuh)

Wirt

  • 65
  • 32
  • 15
  • 2
Maus

Klonalität

  • 65
  • 45
  • 3
Monoklonal

Konjugat

  • 45
  • 9
  • 7
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NCR1 Antikörper ist unkonjugiert

Applikation

  • 52
  • 39
  • 24
  • 14
  • 13
  • 13
  • 10
  • 9
  • 7
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Klon

AKS1
  • Spezifität

    This Low Endotoxin antibody is specific for Bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (2).

    Aufreinigung

    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

    Endotoxin-Niveau

    Low Endotoxin

    Immunogen

    Fusion protein consisting of the extracellular region of Bovine CD335. Remarks: Spleen cells from immunised Balb/c mice were fused with cells of the NS-0 myeloma cell line.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow Cytometry: Use 10 μL of 1/5-1/200 diluted antibody to label 106 cells in 100 μL. Western Blot. Functional Assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: < 0.01EU/ug.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4 containing no preservatives.

    Konservierungsmittel

    Without preservative

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target

    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

    Andere Bezeichnung

    CD335 / NKp46

    Hintergrund

    CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (4). The bovine homologue is expressed on bovine NK cells (2) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Synonyms: LY94, NCR1, NK cell-activating receptor, NKp46, Natural cytotoxicity triggering receptor, Natural killer cell p46-related protei

    Gen-ID

    369024

    NCBI Accession

    NP_899209

    UniProt

    Q863H2

    Pathways

    Regulation of Leukocyte Mediated Immunity
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