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CD8 Antikörper

CD8 Reaktivität: Maus FACS, IHC (fro) Wirt: Ratte Monoclonal YTS105-18 unconjugated

Produktnummer ABIN319570

Datenblatt (PDF)

Target Alle CD8 Antikörper anzeigen

CD8
Reaktivität
209

66

25

12

12

12

9

9

8

8

6

6

6

5

5

5

4

4

3

2

1

1
Maus
Wirt
243

48

36

4
Ratte
Passende Sekundärantikörper
Klonalität
294

30

2
Monoklonal
Konjugat
106

49

38

26

13

7

5

5

5

5

5

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD8 Antikörper ist unkonjugiert
Applikation
288

68

55

52

50

46

32

21

18

17

15

14

8

5

5

4

3

2

2

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität

This antibody recognises a non polymorphic epitope on the CD8 alpha chain. Blocks MHC I dependent T cell responses in vitro and in vivo, and induces transplantation tolerance in combination with CD4 antibodies.

Aufreinigung

Affinity Chromatography on Protein G.

Immunogen

Mouse spleen cells. Spleen cells from an immunised DA rat were fused with cells of the rat Y3/Ag1.2.3. myeloma cell line.

Klon

YTS105-18

Isotyp

IgG2a

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CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PE

anti-CD8 (CD8) (AA 22-187) antibody
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anti-CD8 (CD8) antibody (Biotin)
CD8 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-31 Biotin

anti-CD8 (CD8) antibody (FITC)
CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 FITC

anti-CD8 (CD8) antibody
CD8 Reaktivität: Human IHC, IP, WB, ELISA Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody

anti-CD8 (CD8) antibody (PerCP)
CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PerCP

anti-CD8 (CD8) antibody (APC)
CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 APC

anti-CD8 (CD8) antibody (PE)
CD8 Reaktivität: Cat FACS Wirt: Maus Monoclonal fCD8 PE

Applikationshinweise

Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD8

Andere Bezeichnung

CD8 (CD8 Produkte)

Hintergrund

CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds. It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

Gen-ID

12525

NCBI Accession

NP_001074579

UniProt

P01731